In vivo transformation of human skin with human papillomavirus type 11 from condylomata acuminata

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In vivo transformation of human skin with human papillomavirus type 11 from condylomata acuminata.

Human papillomaviruses (HPVs) have been implicated in the development of a number of human malignancies, but direct tests of their involvement have not been possible. We describe a system in which human skin from various sites was infected with HPV type 11 (HPV-11) extracted from vulvar condylomata and was grafted beneath the renal capsule of athymic mice. Most of the skin grafts so treated und...

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Use of human papillomavirus type 11 virions in an ELISA to detect specific antibodies in humans with condylomata acuminata.

Human papillomavirus types 6 and 11 (HPV-6 and HPV-11) are the major aetiological agents of condylomata acuminata. Serological studies of this disease have been difficult to perform and interpret because native, type-specific antigens have not been available. In particular, since these viruses have not been propagated in vitro and sufficient quantities of virions are not present in lesions, vir...

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Detection of multiple human papillomavirus types in Condylomata acuminata lesions from otherwise healthy and immunosuppressed patients.

Condylomata acuminata, or genital warts, are proliferative lesions of genital epithelium caused by human papillomavirus (HPV) infection. HPV types 6 and 11 are most often detected in these lesions. Genital lesions consistent with exophytic condylomata acuminata were removed by excision biopsy from 65 patients, 41 of whom were otherwise healthy individuals (control group) and 24 of whom had cond...

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Condylomata acuminata and human genital cancer.

1. Almeida, J. D., Oriel, J. D., and Stannard, L. M. Characterization of the Virus Found in Human Genital Warts. Microbios, 3: 225-232, 1969. 2. Bauer, K. M., and Friederich H. C. Peniscarcinom auf dem Boden vorbehandelter Condylomata acuminata. Z. Haut-Geschlechlskrankh., 39:150-163, 1965. 3. Dawson, D. F., Duckworth, J. K., Bernhardt, H. and Young, J. M. Giant Condyloma and Verrucous Carcinom...

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Human papillomavirus genotype distribution in external acuminata condylomata: a Large French National Study (EDiTH IV).

BACKGROUND External acuminata condylomata (EAC) are among the most common sexually transmitted diseases. Although it is understood that low-risk human papillomavirus (HPV) genotypes 6 and 11 are associated with EAC, there have only been a few, small, published studies reporting the genotype-specific prevalence of HPV. The objective of our study was to assess the prevalence of HPV genotypes for ...

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ژورنال

عنوان ژورنال: Journal of Virology

سال: 1986

ISSN: 0022-538X,1098-5514

DOI: 10.1128/jvi.59.2.369-376.1986